Maintaining human health and safety in habitations outside of Earth, especially for long-duration trips, is a major challenge. The Office of the Inspector General has found that NASA should do more to protect astronaut health, particularly on long-duration missions to deep space 1.
Long-term exposure to zero gravity has many negative health impacts, including bone and muscle loss 2. The limited evidence available suggests that low but nonzero gravity, such as seen on Mars, has negative impacts as well, but not as severe as those of microgravity 3.
Rotation in an orbital habitat could simulate gravity, but at the cost of introducing a Coriolis force. The radius of rotation would have to be at least an estimated 12-24 meters before the Coriolis force is tolerable 4.
Without the protection of Earth's atmosphere and magnetic field, exposure to radiation is a concern for long-duration missions, especially beyond low-Earth orbit. Radiation exposure is estimated as follows.
Currently NASA protects astronauts from radiation by limiting overall flight time, spacewalk time, and scheduling spacewalk time for periods of low solar activity. Radiation shielding, diets rich in Vitamins C, A, and D, and drugs also protect astronaut health 6.
The combination of unusual lighting patterns, work schedules, and gravity load disrupts astronauts' sleep on the International Space Station. The disruption of the circadian rhythm causes health damage, and it also degrades the ability of astronauts to perform their jobs well.
Experiences have found that the circadian rhythm can be adjusted to a 23.5 hour day or a 24.65 hour day, but cannot be adjusted to a 21 hour day or a 27 hour day 7. Astronauts on the International Space Station deal with sleep challenges through medication 7.
NASA is conducting the Lighting Effects study, which is hoped to develop a lighting regimen, with solid state lighting and LEDs, that better mimics a natural 24 hour day/night cycle and enables better sleep by astronauts 8.
NASA has in place training and procedures for certan non-emergency and some common emergency medical treatment in space 9, but some emergencies cannot be adequately addressed with the limited training and equipment available. On long-duration submarine missions, an average of 2.3 medical evacuations are needed for every 1000 person-months 10. Based on experience with long-duration activities, such as submarine missions, Antarctic missions, mountain climbing, and present-day space missions, it is estimated that a 6 person crew on a 2.5 year Mars mission would require an average of 0.9 medical evacuations 10.
For a long-duration mission, especially one far from Earth for which communication will be severely delayed, might inflict psychological stress on astronauts 11. Evidence from the Space Shuttle program and the Mir space station suggests that such stress may materialize 12.
Research has also found positive effects, such a greater sense of appreciation, spirituality, and power after space flight 13. These effects, and the tendency to see greater unity on Earth after spaceflight, have been termed the overview effect 14.
Office of the Inspector General. "NASA's Efforts to Manage Health and Human Performance Risks for Space Exploration". Office of Audits. October 2015. ↩
Iwase, S., Nishimura, N., Tanaka, K., Mano, T. "Effects of Microgravity on Human Physiology". Chapter of Beyond LEO - Human Health Issues for Deep Space Exploration. February 2020. ↩
Clément, G. "International roadmap for artificial gravity research". npj Microgravity 3: 29. November 2017. ↩
Clément, G. R., Bukley, A. P., Paloski, W. H. "Artificial gravity as a countermeasure for mitigating physiological deconditioning during long-duration space missions". Frontiers in Systems Neuroscience 9: 92. June 2015. ↩
International Commission on Radiological Protection. "The 2007 Recommendations of the International Commission on Radiological Protection". ICRP Publication 103. Ann. ICRP 37(2-4). 2007. ↩
Lloyd, C. W., Townsend, S., Reeves, K. K., Fitzpatrick, M. S., Frassanito, J., Mulvaney, J., Sauls, B. "Space Radiation". National Aeronautics and Space Administration. Accessed September 16, 2021. ↩ ↩2
Guo, J., Qu, W., Chen, S., Chen, X., Lv, K., Huang, Z., Wu, Y. "Keeping the right time in space: importance of circadian clock and sleep for physiology and performance of astronauts". Military Medical Research 1(1), pp. 1-7. December 2014. ↩ ↩2
Lockley, S. W., Brainard, G. C. "Lighting Effects". NASA. 2016. ↩
SpaceRef. "Routine and Emergency Medical Operations". Accessed September 17, 2021. ↩
Risin, D. "Risk of Inability to Adequately Treat an Ill or Injured Crew Member". NASA Johnson Space Center. 2009. ↩ ↩2
Weed, W. S. "Can We Go to Mars Without Going Crazy?". Discover Magazine. May 2001. ↩
Kanas, N., Salnitskiy, V., Weiss, D. S., Grund, E. M., Gushin, V., Kozerenko, O., Sled, A., Bostrom, A., Marmar, C. R. "Crewmember and ground personnel interactions over time during Shuttle/Mir space missions". Aviation, Space, and Environmental Medicine 72(5), pp. 453-461. 2001. ↩
Suedfeld, P., Legkaia, K., Brcic, J. "Changes in the hierarchy of value references associated with flying in space". Journal of Personality 78(5), pp. 1411-1436. October 2010. ↩
White, F. The Overview Effect: Space Exploration and Human Evolution. ISBN-13: 978-1563472602. 1987. ↩